ETBR Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | ETBR Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | ETBR |
| Recommended applications | ELISA, IHC-p, WB |
| Reactivity | Human |
| Immunogen | Synthesized peptide derived from ETBR at AA range: 31-80 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP10690 |
Additional information
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The protein encoded by EDNRB (endothelin receptor type B) is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for EDNRB.
Endothelin B receptor (ET-B) (ET-BR) (Endothelin receptor non-selective type)
Human: P24530, Mouse: P48302
Human: 1910, Mouse: 13618