FAK(Phospho-Ser732) Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

FAK

Host

Rabbit

Isotype

IgG

Target protein

PTK2

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human FAK (Phospho-Ser732)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP13494

Additional information

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene| but the full-length natures of only four of them have been determined.
FAK ,Phospho-Ser732, Focal adhesion kinase 1, FADK 1, EC 2.7.10.2, Focal adhesion kinase-related nonkinase, FRNK, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK, pp125FAK
Human: Q05397
Human: 5747