Product information
Price | €175, €275, €395 |
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Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
Short name | FAM111B Antibody |
Host | Rabbit |
Isotype | IgG |
Target protein | FAM111B |
Recommended applications | ELISA, IHC-p |
Reactivity | Human |
Immunogen | The antiserum was produced against synthesized peptide derived from human F111B. AA range:281-330 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
Storage | -20°C for 1 year |
Product code | MB-AP10670 |
Additional information
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FAM111B encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin-like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.
FAM111B, CANP, Protein FAM111B, Cancer-associated nucleoprotein
Human: Q6SJ93
Human: 374393