Product information
Price | €240, €410 |
---|---|
Size | 50 µl/µg | 100 µl/µg |
Short name | Fps, Tyrosine-protein kinase Fes |
Host | Mouse |
Isotype | IgG |
Target protein | FES |
Recommended applications | ELISA, IF, IHC-p, WB |
Reactivity | Human |
Immunogen | Purified recombinant fragment of Fer expressed in E. Coli. |
Purification | Affinity purification |
Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
Storage | -20°C for 1 year |
Product code | MB-AM10298 |
Additional information
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This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.
FES, FPS, Tyrosine-protein kinase Fes, Fps, Feline sarcoma, Fujinami avian sarcoma oncogene homolog, Proto-oncogene c-Fes, Proto-oncogene c-Fps, p93c-fes
Human: P07332, Mouse: P16879
Human: 2242