FGFR-4 Monoclonal Antibody
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Product information
| Price | €240, €410 |
|---|---|
| Size | 50 µl/µg | 100 µl/µg |
| Short name | Fibroblast growth factor receptor 4 |
| Host | Mouse |
| Isotype | IgG |
| Target protein | FGFR4 |
| Recommended applications | ELISA, IF, IHC-p, WB |
| Reactivity | Human |
| Immunogen | Purified recombinant fragment of FGFR-4 expressed in E. Coli. |
| Purification | Affinity purification |
| Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AM10296 |
Additional information
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The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgII
FGFR4, JTK2, TKF, Fibroblast growth factor receptor 4, FGFR-4, CD antigen CD334
Human: P22455, Mouse: Q03142
Human: 2264