FH Monoclonal Antibody(7F1)

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

Fumarate hydratase, mitochondrial

Host

Mouse

Isotype

IgG

Target protein

FH

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic Peptide of FH

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Formulation

PBS; pH 7.4; containing 0.5%BSA; 0.02% sodium azide as Preservative and 50% Glycerol.

Storage

-20°C for 1 year

Product code

MB-AM10530

Additional information

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Fumarate hydratase, mitochondrial, Fumarase, EC 4.2.1.2
Human: P07954, Mouse: P97807, Rat: P14408
Human: 2271, Mouse: 14194