Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Fumarate hydratase, mitochondrial |
| Host | Mouse |
| Isotype | IgG |
| Target protein | FH |
| Recommended applications | ICC, IF, IHC-p, WB |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic Peptide of FH |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Formulation | PBS; pH 7.4; containing 0.5%BSA; 0.02% sodium azide as Preservative and 50% Glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AM10530 |
Additional information
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The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Fumarate hydratase, mitochondrial, Fumarase, EC 4.2.1.2
Human: P07954, Mouse: P97807, Rat: P14408
Human: 2271, Mouse: 14194
