Product information
Price | €175, €275, €395 |
---|---|
Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
Short name | FOP Antibody |
Host | Rabbit |
Isotype | IgG |
Target protein | FGFR1OP |
Recommended applications | ELISA, IF, IHC-p, WB |
Reactivity | Human, Mouse, Rat |
Immunogen | The antiserum was produced against synthesized peptide derived from human FGFR1 Oncogene Partner. AA range:341-390 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
Storage | -20°C for 1 year |
Product code | MB-AP10618 |
Additional information
Prev
Next
FGFR1OP encodes a largely hydrophilic centrosomal protein, FGFR1 oncogene partner, that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
FGFR1OP, FOP, FGFR1 oncogene partner
Human: O95684, Mouse: Q66JX5, Rat: Q4V7C1
Human: 11116, Mouse: 75296, Rat: 683722