GABA A Receptor alpha4 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Gamma-aminobutyric acid receptor subunit alpha-4 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | GABRA4 |
| Recommended applications | IF, IHC-p, WB |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic Peptide of GABA A Receptor α4 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12747 |
Additional information
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Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.
Gamma-aminobutyric acid receptor subunit alpha-4 ,GABA,A receptor subunit alpha-4, GABRA4, Gamma-aminobutyric acid receptor subunit alpha-4, GABA,A receptor subunit alpha-4
Human: P48169, Mouse: Q9D6F4, Rat: P28471
Human: 2557