Product information
Price | €175, €275, €395 |
---|---|
Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
Short name | GCG Antibody |
Host | Rabbit |
Isotype | IgG |
Target protein | GCG |
Recommended applications | ELISA, IF, IHC-p, WB |
Reactivity | Human, Monkey, Mouse, Rat |
Immunogen | The antiserum was produced against synthesized peptide derived from human Glucagon. AA range:61-110 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
Storage | -20°C for 1 year |
Product code | MB-AP10533 |
Additional information
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Glucagon encoded by GCG is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
GCG, Glucagon
Human: P01275, Mouse: P55095, Rat: P06883
Human: 2641, Mouse: 14526