Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Eukaryotic translation initiation factor 2-alpha kinase 4 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | EIF2AK4 |
| Recommended applications | ELISA, IF, IHC-p |
| Reactivity | Human, Mouse |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GCN2 around the phosphorylation site of Thr899. AA range:865-914 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12738 |
Additional information
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This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.
Eukaryotic translation initiation factor 2-alpha kinase 4, EIF2AK4, GCN2, KIAA1338, Eukaryotic translation initiation factor 2-alpha kinase 4, GCN2-like protein
Human: Q9P2K8, Mouse: Q9QZ05
Human: 440275, Mouse: 27103
