GDF-9 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | GDF-9 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | GDF9 |
| Recommended applications | ELISA, IHC-p, WB |
| Reactivity | Human |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GDF-9. AA range:273-322 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP10517 |
Additional information
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GDF9 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Growth/differentiation factor 9 regulates ovarian function. Reduced expression of GDF9 may be associated with polycystic ovary syndrome and mutations in this gene may be more common in mothers of dizygotic twins.
GDF9, Growth/differentiation factor 9, GDF-9
Human: O60383, Mouse: Q07105
Human: 2661