Product information
Price | €175, €275, €395 |
---|---|
Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
Short name | Histone H3 Antibody |
Host | Rabbit |
Isotype | IgG |
Target protein | HIST1H3A |
Recommended applications | IHC-p, WB |
Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic Peptide of Histone H3 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Formulation | PBS; pH 7.4; containing 0.02% sodium azide as Preservative and 50% Glycerol. |
Storage | -20°C for 1 year |
Product code | MB-AP10350 |
Additional information
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ, Histone H3.1, Histone H3/a, Histone H3/b
Human: P68431/Q71DI3/P84243/Q6NXT2, Rat: Q6LED0/P84245
Human: 8350/8351/8352/8353/8354/8355/8356/8357/8358/8968/126961/333932/653604/3020/3021/440093, Mouse: 319152/15077/15078/625328, Rat: 291159/100361558