Product information
Price | €175, €275, €395 |
---|---|
Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
Short name | Histone H4 (Acetyl Lys8) Antibody |
Host | Rabbit |
Isotype | IgG |
Target protein | HIST1H4A |
Recommended applications | ELISA, IF, IHC-p, WB |
Reactivity | Human, Monkey, Mouse, Rat |
Immunogen | The antiserum was produced against synthesized peptide derived from human Histone H4 around the acetylated site of Lys8. AA range:1-50 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
Storage | -20°C for 1 year |
Product code | MB-AP10344 |
Additional information
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST4H4 is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from HIST4H4 lack polyA tails; instead, they contain a palindromic termination element.
HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HI
Human: P62805, Mouse: P62806, Rat: P62804
Human: 121504/554313/8294/8359/8360/8361/8362/8363/8364/8365/8366/8367/8368/8370, Mouse: 1.00041e+008, Rat: 1.00361e+008