Integrin AlphaV Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

Integrin alphaV Antibody

Host

Rabbit

Isotype

IgG

Target protein

ITGAV

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human Integrin alphaV. AA range:755-804

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP10162

Additional information

Integrin alpha-V encoded by ITGAV belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
ITGAV, MSK8, VNRA, Integrin alpha-V, Vitronectin receptor subunit alpha, CD antigen CD51
Human: P06756, Mouse: P43406
Human: 3685, Mouse: 16410