KIR3.1(Phospho Ser185) Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | G protein-activated inward rectifier potassium channel 1 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | KCNJ3 |
| Recommended applications | ELISA, ICC, IF, IHC-p, WB |
| Reactivity | Human, Monkey, Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GIRK1/KIR3.1/KCNJ3 around the phosphorylation site of Ser185. AA range:151-200 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12555 |
Additional information
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Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, at
G protein-activated inward rectifier potassium channel 1, KCNJ3, GIRK1, G protein-activated inward rectifier potassium channel 1, GIRK-1, Inward rectifier K,+ channel Kir3.1, Potassium channel, inwardly rectifying subfamily J member 3
Human: P48549, Mouse: P63250, Rat: P63251
Human: 3760, Mouse: 16519, Rat: 50599