Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | KLF12 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | KLF12 |
| Recommended applications | ELISA, IHC-p, WB |
| Reactivity | Human, Mouse |
| Immunogen | Synthesized peptide derived from the Internal region of human KLF12. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP10073 |
Additional information
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Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. Krueppel-like factor 12 encoded by KLF12 is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
KLF12, AP2REP, HSPC122, Krueppel-like factor 12, Transcriptional repressor AP-2rep
Human: Q9Y4X4, Mouse: O35738
Human: 11278, Mouse: 16597
