Product information
Price | €175, €275, €395 |
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Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
Short name | KLHL3 Antibody |
Host | Rabbit |
Isotype | IgG |
Target protein | KLHL3 |
Recommended applications | ELISA, IF, IHC-p, WB |
Reactivity | Human |
Immunogen | The antiserum was produced against synthesized peptide derived from human KLHL3. AA range:10-59 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
Storage | -20°C for 1 year |
Product code | MB-AP10069 |
Additional information
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KLHL3 is ubiquitously expressed and encodes kelch like family member 3 which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
KLHL3, KIAA1129, Kelch-like protein 3
Human: Q9UH77, Mouse: E0CZ16
Human: 26249