KOR-1 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | KOR-1 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | OPRK1 |
| Recommended applications | ELISA, IHC-p, WB |
| Reactivity | Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from mouse KOR-1. AA range:331-380 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP10068 |
Additional information
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OPRK1 encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in OPRK1 have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
OPRK1, OPRK, Kappa-type opioid receptor, K-OR-1, KOR-1
Human: P41145, Mouse: P33534, Rat: P34975
Human: 4986, Mouse: 18387, Rat: 29335