Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | 44257 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | MARCH2 |
| Recommended applications | ELISA, IF, IHC-p |
| Reactivity | Human |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MARCH2. AA range:191-240 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP15232 |
Additional information
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MARCH2 (membrane associated ring-CH-type finger 2) is a member of the MARCH family of membrane-bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking.
MARCH2, RNF172, HSPC240, E3 ubiquitin-protein ligase MARCH2, Membrane-associated RING finger protein 2, Membrane-associated RING-CH protein II, MARCH-II, RING finger protein 172
Human: Q9P0N8, Mouse: Q99M02
Human: 51257
