MMP-8 Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

MMP-8 Antibody

Host

Rabbit

Isotype

IgG

Target protein

MMP8

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human MMP-8. AA range:418-467

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP15124

Additional information

MMP8 encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. Alternative splicing results in multiple transcript variants.
MMP8, CLG1, Neutrophil collagenase, Matrix metalloproteinase-8, MMP-8, PMNL collagenase, PMNL-CL
Human: P22894, Mouse: O70138, Rat: O88766
Human: 4317, Mouse: 17394, Rat: 63849