MSH2 Monoclonal Antibody
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Product information
| Price | €240, €410 |
|---|---|
| Size | 50 µl/µg | 100 µl/µg |
| Short name | DNA mismatch repair protein Msh2 |
| Host | Mouse |
| Isotype | IgG |
| Target protein | MSH2 |
| Recommended applications | ELISA, ICC, IF, IHC-p, WB |
| Reactivity | Human, Monkey |
| Immunogen | Purified recombinant fragment of human MSH2 expressed in E. Coli. |
| Purification | Affinity purification |
| Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AM10180 |
Additional information
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This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
MSH2, DNA mismatch repair protein Msh2, hMSH2, MutS protein homolog 2
Human: P43246, Mouse: P43247
Human: 4436