Myosin VI Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

Myosin VI Antibody

Host

Rabbit

Isotype

IgG

Target protein

MYO6

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from Myosin VI . at AA range: 40-120

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP15016

Additional information

MYO6 encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The unconventional myosin-VI consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
MYO6, KIAA0389, Unconventional myosin-VI, Unconventional myosin-6
Human: Q9UM54, Mouse: Q64331
Human: 4646