NFATc4 Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

NFATc4 Antibody

Host

Rabbit

Isotype

IgG

Target protein

NFATC4

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human NFAT3. AA range:642-691

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP14922

Additional information

NFATC4 encodes a member of the nuclear factor of activated T cells (NFAT) protein family. Nuclear factor of activated T-cells cytoplasmic 4 is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants.
NFATC4, NFAT3, Nuclear factor of activated T-cells, cytoplasmic 4, NF-ATc4, NFATc4, T-cell transcription factor NFAT3, NF-AT3
Human: Q14934, Mouse: Q8K120
Human: 4776, Mouse: 73181