ORAOV1 Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

ORAOV1 Antibody

Host

Rabbit

Isotype

IgG

Target protein

ORAOV1

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human ORAV1. AA range:81-130

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP14801

Additional information

SLC22A18 is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15. , an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. SLC22A18 is imprinted, with preferential expression from the maternal allele. Mutations in SLC22A18 have been found in Wilms' tumor and lung cancer. Solute carrier family 22 member 18 may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described.
ORAOV1, TAOS1, Oral cancer-overexpressed protein 1, Tumor-amplified and overexpressed sequence 1
Human: Q8WV07, Mouse: Q8CH62
Human: 220064