p19 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | p19 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | CDKN2D |
| Recommended applications | ELISA, IHC-p |
| Reactivity | Human |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CDKN2D. AA range:96-145 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP14787 |
Additional information
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The cyclin dependent kinase inhibitor 2D encoded by CDKN2D is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.
CDKN2D, Cyclin-dependent kinase 4 inhibitor D, p19-INK4d
Human: P55273, Mouse: Q60773
Human: 1032