P2X3 Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

P2X3 Antibody

Host

Rabbit

Isotype

IgG

Target protein

P2RX3

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human P2RX3. AA range:81-130

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP14780

Additional information

The product of P2RX3 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
P2RX3, P2X purinoceptor 3, P2X3, ATP receptor, Purinergic receptor
Human: P56373, Mouse: Q3UR32, Rat: P49654
Human: 5024, Mouse: 228139, Rat: 81739