PCNA Monoclonal Antibody(12D10)
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Proliferating cell nuclear antigen |
| Host | Mouse |
| Isotype | IgG |
| Target protein | PCNA |
| Recommended applications | ICC, IF, IHC-p, WB |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic Peptide of PCNA |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Formulation | PBS; pH 7.4; containing 0.5%BSA; 0.02% sodium azide as Preservative and 50% Glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AM10509 |
Additional information
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The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
PCNA, Proliferating cell nuclear antigen, PCNA, Cyclin
Human: P12004, Mouse: P17918, Rat: P04961
Human: 5111, Mouse: 18538, Rat: 25737