Product information
Price | €240, €410 |
---|---|
Size | 50 µl/µg | 100 µl/µg |
Short name | mitochondrial, Pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1 |
Host | Mouse |
Isotype | IgG |
Target protein | PDK1 |
Recommended applications | ELISA, FCM, ICC, IF, IHC-p, WB |
Reactivity | Human, Monkey, Rat |
Immunogen | Purified recombinant fragment of human PDK1 expressed in E. Coli. |
Purification | Affinity purification |
Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
Storage | -20°C for 1 year |
Product code | MB-AM10137 |
Additional information
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Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
PDK1, PDHK1, Pyruvate dehydrogenase (lipoamide) kinase isozyme 1, mitochondrial, Pyruvate dehydrogenase kinase isoform 1
Human: Q15118, Mouse: Q8BFP9, Rat: Q63065
Human: 5163