PDK1 Monoclonal Antibody

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Product information

Price

€240, €410

Size

50 µl/µg | 100 µl/µg

Short name

mitochondrial, Pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1

Host

Mouse

Isotype

IgG

Target protein

PDK1

Reactivity

Human, Monkey, Rat

Immunogen

Purified recombinant fragment of human PDK1 expressed in E. Coli.

Purification

Affinity purification

Formulation

Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol.

Storage

-20°C for 1 year

Product code

MB-AM10137

Additional information

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
PDK1, PDHK1, Pyruvate dehydrogenase (lipoamide) kinase isozyme 1, mitochondrial, Pyruvate dehydrogenase kinase isoform 1
Human: Q15118, Mouse: Q8BFP9, Rat: Q63065
Human: 5163