Phospho-ATP-citrate synthase (S455) Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Phospho-ATP-citrate synthase (S455) Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | ACLY |
| Recommended applications | ELISA, IHC-p, WB |
| Reactivity | Human, Monkey, Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ATP-Citrate Lyase around the phosphorylation site of Ser454. AA range:420-469 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS; pH 7.4; containing 0.02% Sodium Azide as preservative; 1% BSA as stablizer and 50% Glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AP13621 |
Additional information
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ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
ACLY, ATP-citrate synthase, ATP-citrate, pro-S-)-lyase, ACL, Citrate cleavage enzyme
Human: P53396, Mouse: Q91V92, Rat: P16638
Human: 47, Mouse: 104112, Rat: 24159