Phospho-B23 (T234) Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Phospho-B23 (T234) Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | NPM1 |
| Recommended applications | ELISA, IHC-p, WB |
| Reactivity | Human, Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NPM around the phosphorylation site of Thr234. AA range:201-250 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS; pH 7.4; containing 0.02% Sodium Azide as preservative; 1% BSA as stablizer and 50% Glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AP13647 |
Additional information
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NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified. Alternative splicing results in multiple transcript variants.
NPM1, NPM, Nucleophosmin, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin
Human: P06748, Mouse: Q61937, Rat: P13084
Human: 4869, Mouse: 18148, Rat: 25498