Phospho-BID (S78) Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

Phospho-BID (S78) Antibody

Host

Rabbit

Isotype

IgG

Target protein

BID

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human BID around the phosphorylation site of Ser78. AA range:44-93

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP13664

Additional information

BID (BH3 interacting domain death agonist) encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
BID, BH3-interacting domain death agonist, p22 BID, BID
Human: P55957, Mouse: P70444
Human: 637, Mouse: 12122