Phospho-Caldesmon (S759) Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Phospho-Caldesmon (S759) Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | CALD1 |
| Recommended applications | ELISA, IHC-p |
| Reactivity | Human, Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Caldesmon around the phosphorylation site of Ser759. AA range:725-774 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in 0.01M Phosphate Buffered Saline; pH 7.2; containing 1% BSA; 50% glycerol; 0.02% Sodium Azide |
| Storage | -20°C for 1 year |
| Product code | MB-AP13549 |
Additional information
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CALD1 (caldesmon 1) encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
CALD1, CAD, CDM, Caldesmon, CDM
Human: Q05682, Rat: Q62736
Human: 800, Rat: 25687