Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Phospho-Caldesmon (S789) Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | CALD1 |
| Recommended applications | ELISA, IF, IHC-p, WB |
| Reactivity | Human, Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Caldesmon around the phosphorylation site of Ser789. AA range:744-793 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in 0.01M Phosphate Buffered Saline; pH 7.2; containing 1% BSA; 50% glycerol; 0.02% Sodium Azide |
| Storage | -20°C for 1 year |
| Product code | MB-AP13592 |
Additional information
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CALD1 encodes a calmodulin- and actin-binding protein (caldesmon 1) that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca (2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+)- dependent inhibition of smooth muscle contraction. Alternative splicing of CALD1 results in multiple transcript variants encoding distinct isoforms.
CALD1, CAD, CDM, Caldesmon, CDM
Human: Q05682, Rat: Q62736
Human: 800, Rat: 25687
