PP1 Alpha Monoclonal Antibody
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Product information
| Price | €240, €410 |
|---|---|
| Size | 50 µl/µg | 100 µl/µg |
| Short name | Serine, threonine-protein phosphatase PP1-alpha catalytic subunit |
| Host | Mouse |
| Isotype | IgG |
| Target protein | PPP1CA |
| Recommended applications | IF, IHC-p, WB |
| Reactivity | Human, Mouse, Pig, Rabbit, Rat |
| Immunogen | Purified recombinant human PP1α protein fragments expressed in E.coli. |
| Purification | Affinity purification |
| Formulation | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4; 150 mM NaCl) with 0.2% sodium azide; 50% glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AM10120 |
Additional information
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The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
PPP1CA, PPP1A, Serine, threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A
Human: P62136, Mouse: P62137, Rat: P62138
Human: 5499, Mouse: 19045, Rat: 24668