PRK2 Monoclonal Antibody

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Product information

Price

€240, €410

Size

50 µl/µg | 100 µl/µg

Short name

Serine, threonine-protein kinase N2

Host

Mouse

Isotype

IgG

Target protein

PKN2

Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Purified recombinant fragment of human PRK2 expressed in E. Coli.

Purification

Affinity purification

Formulation

Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol.

Storage

-20°C for 1 year

Product code

MB-AM10113

Additional information

Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation:Activated by lipids, particularly cardiolipin and to a lesser extent by other acidic phospholipids and unsaturated fatty acids. Two specific sites, Thr-816 (activation loop of the kinase domain) and Thr-958 (turn motif), need to be phosphorylated for its full activation.,function:Exhibits a preference for highly basic protein substrates.,PTM:Activated by limited proteolysis with trypsin.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 C2 domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 REM (Hr1) repeats.,
PKN2, PRK2, PRKCL2, Serine, threonine-protein kinase N2, PKN gamma, Protein kinase C-like 2, Protein-kinase C-related kinase 2
Human: Q16513, Mouse: Q8BWW9, Rat: O08874
Human: 5586, Mouse: 109333