PTH/PTHrP-R Monoclonal Antibody
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Product information
| Price | €240, €410 |
|---|---|
| Size | 50 µl/µg | 100 µl/µg |
| Short name | kparathyroid hormone-related peptide receptor, Parathyroid hormone |
| Host | Mouse |
| Isotype | IgG |
| Target protein | PTH1R |
| Recommended applications | ELISA, ICC, IF, IHC-p, WB |
| Reactivity | Human |
| Immunogen | Purified recombinant fragment of human PTH/PTHrP-R expressed in E. Coli. |
| Purification | Affinity purification |
| Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AM10106 |
Additional information
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The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
PTH1R, PTHR, PTHR1, Parathyroid hormone, parathyroid hormone-related peptide receptor, PTH, PTHrP type I receptor, PTH, PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor
Human: Q03431, Mouse: P41593
Human: 5745