PTN13 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Tyrosine-protein phosphatase non-receptor type 13 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | PTPN13 |
| Recommended applications | IF, IHC-p |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12255 |
Additional information
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, ha
Tyrosine-protein phosphatase non-receptor type 13 ,EC 3.1.3.48,Fas-associated protein-tyrosine phosphatase 1,FAP-1,PTP-BAS,Protein-tyrosine phosphatase 1E,PTP-E1,hPTPE1,Protein-tyrosine
Human: Q12923, Mouse: Q64512
Human: 5783