Rac GAP1(Phospho Ser387) Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Rac GTPase-activating protein 1 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | RACGAP1 |
| Recommended applications | ELISA, ICC, IF, IHC-p, WB |
| Reactivity | Human, Monkey, Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GTPase Activating Protein around the phosphorylation site of Ser387. AA range:353-402 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12250 |
Additional information
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This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.
Rac GTPase-activating protein 1, RACGAP1, KIAA1478, MGCRACGAP, Rac GTPase-activating protein 1, Male germ cell RacGap, MgcRacGAP, Protein CYK4 homolg, CYK4, HsCYK-4
Human: Q9H0H5, Mouse: Q9WVM1
Human: 29127, Mouse: 26934