Product information
Price | €240, €410 |
---|---|
Size | 50 µl/µg | 100 µl/µg |
Short name | Protein S100-B |
Host | Mouse |
Isotype | IgG |
Target protein | S100B |
Recommended applications | ELISA, IF, IHC-p, WB |
Reactivity | Human |
Immunogen | Purified recombinant fragment of S-100 Beta expressed in E. Coli. |
Purification | Affinity purification |
Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
Storage | -20°C for 1 year |
Product code | MB-AM10091 |
Additional information
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The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21| however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy
S100B, Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B
Human: P04271, Mouse: P50114
Human: 6285