SP-100 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | SP-100 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | SP100 |
| Recommended applications | ELISA, IHC-p, WB |
| Reactivity | Human |
| Immunogen | Synthesized peptide derived from SP-100 . at AA range: 250-330 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP14154 |
Additional information
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SP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100; one of which encodes a high-mobility group protein.
SP100, Nuclear autoantigen Sp-100, Lysp100b, Nuclear dot-associated Sp100 protein, Speckled 100 kDa
Human: P23497, Mouse: O35892
Human: 6672