SR-2A Polyclonal Antibody
Prices are excluding VAT and shipping costs
Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | SR-2A Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | HTR2A |
| Recommended applications | ELISA, IF, IHC-p |
| Reactivity | Human |
| Immunogen | The antiserum was produced against synthesized peptide derived from human 5-HT-2A. AA range:422-471 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP14135 |
Additional information
Prev
Next
HTR2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in HTR2A are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
HTR2A, HTR2, 5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, Serotonin receptor 2A
Human: P28223, Mouse: P35363
Human: 3356