SREBP-1(Phospho Ser439) Polyclonal Antibody
Prices are excluding VAT and shipping costs
Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Sterol regulatory element-binding protein 1 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | SREBF1 |
| Recommended applications | ELISA, IF, IHC-p, WB |
| Reactivity | Human, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SREBP-1 around the phosphorylation site of Ser439. AA range:405-454 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP13315 |
Additional information
Prev
Next
This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1)| which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage| the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor| and the mature nuclear form is rapidly catabolized| thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17.
Sterol regulatory element-binding protein 1, SREBF1, BHLHD1, SREBP1, Sterol regulatory element-binding protein 1, SREBP-1, Class D basic helix-loop-helix protein 1, bHLHd1, Sterol regulatory element-binding transcription factor 1
Human: P36956, Mouse: Q9WTN3, Rat: P56720
Human: 6720, Rat: 78968