TAF II p100 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | TAF II p100 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | TAF5 |
| Recommended applications | ELISA, IHC-p, WB |
| Reactivity | Human, Mouse |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TAF5. AA range:381-430 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP14051 |
Additional information
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. Transcription initiation factor TFIID subunit 5 that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF5 encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex. This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex. Alternative splicing results in multiple transcript variants.
TAF5, TAF2D, Transcription initiation factor TFIID subunit 5, Transcription initiation factor TFIID 100 kDa subunit, TAF(II)100, TAFII-100, TAFII100
Human: Q15542, Mouse: Q8C092
Human: 6877, Mouse: 226182