TBL1XR1 Monoclonal Antibody
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Product information
| Price | €240, €410 |
|---|---|
| Size | 50 µl/µg | 100 µl/µg |
| Short name | F-box-like, WD repeat-containing protein TBL1XR1 |
| Host | Mouse |
| Isotype | IgG |
| Target protein | TBL1XR1 |
| Recommended applications | ICC, IF, IHC-p, WB |
| Reactivity | Bovine, Chicken, Dog, Human, Mouse, Pig, Rat, Zebrafish |
| Immunogen | Purified recombinant human TBL1XR1 protein fragments expressed in E.coli. |
| Purification | Affinity purification |
| Formulation | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4; 150 mM NaCl) with 0.2% sodium azide; 50% glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AM10058 |
Additional information
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This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.
TBL1XR1, IRA1, TBLR1, F-box-like, WD repeat-containing protein TBL1XR1, Nuclear receptor corepressor, HDAC3 complex subunit TBLR1, TBL1-related protein 1, Transducin beta-like 1X-related protein 1
Human: Q9BZK7, Mouse: Q8BHJ5
Human: 79718, Mouse: 81004