Product information
Price | €240, €410 |
---|---|
Size | 50 µl/µg | 100 µl/µg |
Short name | Troponin I cardiac muscle |
Host | Mouse |
Isotype | IgG |
Target protein | TNNI3 |
Recommended applications | ELISA, IF, IHC-p, WB |
Reactivity | Human |
Immunogen | Purified recombinant fragment of Troponin I-C expressed in E. Coli. |
Purification | Affinity purification |
Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
Storage | -20°C for 1 year |
Product code | MB-AM10034 |
Additional information
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Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit| blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I
Human: P19429, Mouse: P48787
Human: 7137