Troponin I-C(Phospho Ser22/S23) Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Troponin I cardiac muscle |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | TNNI3 |
| Recommended applications | ELISA, IF, IHC-p, WB |
| Reactivity | Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from mouse TNNI3 around the phosphorylation site of Ser22 and Ser23. AA range:5-54 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP13294 |
Additional information
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Troponin I (TnI)| along with troponin T (TnT) and troponin C (TnC)| is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch| TnI-skeletal-slow-twitch| and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Troponin I cardiac muscle, TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I
Rat: P23693
Mouse: 21954, Rat: 29248