VE-Cadherin mouse Monoclonal Antibody(8E5)

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

CDH5

Host

Mouse

Isotype

IgG

Target protein

CDH5

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic Peptide of VE-Cadherin at AA range of 670-750

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AM10014

Additional information

This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
CDH5
Human: P33151, Mouse: P55284
Human: 1003